@article{mbs:/content/journal/jmm/10.1099/00222615-13-1-57, author = "Brooks, Heather J. L. and O’Grady, F. and McSherry, M. Anne and Cattell, W. R.", title = "UROPATHOGENIC PROPERTIES OF ESCHERICHIA COLI IN RECURRENT URINARY-TRACT INFECTION", journal= "Journal of Medical Microbiology", year = "1980", volume = "13", number = "1", pages = "57-68", doi = "https://doi.org/10.1099/00222615-13-1-57", url = "https://www.microbiologyresearch.org/content/journal/jmm/10.1099/00222615-13-1-57", publisher = "Microbiology Society", issn = "1473-5644", type = "Journal Article", abstract = "SUMMARY Properties of Escherichia coli considered to be important in the pathogenesis of urinary-tract infection were investigated. The following properties were more common in E. coli strains isolated from urinary infections than in periurethral strains from healthy individuals: (i) 0 serogroups 2, 4, 6, 8, 18ab and 75; (ii) high K-antigen titre; (iii) production of haemolysin; (iv) production of fimbriae; (v) fermentation of salicin. The correlation between isolation of a strain from the urinary tract and possession of any single property was not strong; however, strains rich in a combination of these pathogenic properties were rarely isolated from the periurethral area of healthy subjects but were common in urinary infections. Nevertheless, a significant proportion of urinary strains had few pathogenic properties. Strains rich in pathogenic properties were more commonly isolated from upper urinary-tract infections than from lower-tract infections; this indicates that the properties of the invading organism may influence the localisation of infection.", }