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Volume 28, Issue 1

Evaluation of a latex agglutination test for antibodies in seropositive patients Free

Abstract

Summary

A latex agglutination test for antibodies to was compared with micro-immunofluorescence (the reference test for total antibodies); 179 sera were from 115 confirmed cases of Mediterranean Spotted Fever, and 101 were from pregnant women (control group) who had no detectable antibodies by the reference method. The micro-immunofluorescence test for specific IgM antibodies was used to clarify some discordant results. The agreement obtained between latex- and micro-immunofluorescence was 95%. Sensitivity and specificity were 96% and 93% respectively. When micro-immunofluorescence results for specific IgM antibodies were included, these figures rose to 96 and 99%, and agreement was almost 97%. Latex agglutination is a simpler and more rapid technique than micro-immunofluorescence and is suitable for the screening as well as for the titration of antibodies.

  • Received:
  • Accepted:
  • Published Online:
© J. MED. MICROBIOL. 1989
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1989-01-01
2024-04-27
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Evaluation of a latex agglutination test for Rickettsia conorii antibodies in seropositive patients
J. Med. Microbiol. 28, 69 (1989); https://doi.org/10.1099/00222615-28-1-69
/content/journal/jmm/10.1099/00222615-28-1-69
/content/journal/jmm/10.1099/00222615-28-1-69
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