1887

Abstract

Summary

aggregated bovine platelets. The aggregation was paralleled by the haemagglutinating ability of the organism. Treatment of the bacterial cells with antiserum to the homologous purified haemagglutinin reduced the degree of platelet aggregation. Scanning elcctronmicroscopy revealed that little lysis of the affected platelets occurred during the 1-h incubation period. Purified haemagglutinin became bound to the surfaces of the platelet cells as shown by immunofluorescence microscopy. These observations suggest that platelet aggregation is mediated by the haemagglutinin and may be related to the pathogenicity of the bacterium.

Loading

Article metrics loading...

/content/journal/jmm/10.1099/00222615-29-1-13
1989-05-01
2024-04-27
Loading full text...

Full text loading...

/deliver/fulltext/jmm/29/1/medmicro-29-1-13.html?itemId=/content/journal/jmm/10.1099/00222615-29-1-13&mimeType=html&fmt=ahah

References

  1. Czuprynski C. J., Balish E. 1981; Interaction of rat platelets with Listeria monocytogenes. Infection and Immunity 33:103–108
    [Google Scholar]
  2. Dausset J., Collin M., Colombani J. 1960; Immune platelet isoantibodies. Vox Sanguinis 5:4–31
    [Google Scholar]
  3. Forrester L. J., Campbell B. J., Berg J. N., Barrett J. T. 1985; Aggregation of platelets by Fusobacterium necrophorum. Journal of Clinical Microbiology 22:245–249
    [Google Scholar]
  4. Greenblatt J., Boackle J. R., Schwab J. H. 1978; Activation of the alternate complement pathway by peptidoglycan from streptococcal cell wall. Infection and Immunity 19:296–303
    [Google Scholar]
  5. Kanoe M., Iwaki K. 1987; Adherence of Fusobacterium necrophorum to bovine ruminal cells. Journal of Medical Microbiology 23:69–73
    [Google Scholar]
  6. Kanoe M., Nouka K., Toda M. 1984; Isolation of obligate anaerobic bacteria from bovine abscesses in sites other than the liver. Journal of Medical Microbiology 18:365–369
    [Google Scholar]
  7. Kurpiewski G. E., Forrester L. J., Campbell B. J., Barrett J. T. 1983; Platelet aggregation by Streptococcus pyogenes. Infection and Immunity 39:704–708
    [Google Scholar]
  8. Langworth B. F. 1977; Fusobacterium necrophorum: Its characteristics and role as an animal pathogen. Bacteriological Reviews 41:373–390
    [Google Scholar]
  9. Maisch P. A., Calderone R. A. 1981; Role of surface mannan in the adherence of Candida albicans to fibrin-platelet clots formed in vitro. Infection and Immunity 32:92–97
    [Google Scholar]
  10. Morrison D. C., Kline L. F., Oades Z. G., Henson P. M. 1978; Mechanisms of lipopolysaccharide-initiated rabbit platelet responses: alternate complement pathway dependence of the lytic reaction. Infection and Immunity 20:744–751
    [Google Scholar]
  11. Nagai S., Kanoe M., Toda M. 1984; Purification and partial characterization of Fusobacterium necrophorum hemagglutinin. Zentralblatt fur Bakteriologie, Mikrobiologie und Hygiene A 258:232–241
    [Google Scholar]
  12. Rourke F. J., Fan S. S., Wilder M. S. 1979; Anticomplementary activity of tuberculin: relationship to platelet aggregation and lytic response. Infection and Immunity 23:160–167
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jmm/10.1099/00222615-29-1-13
Loading
/content/journal/jmm/10.1099/00222615-29-1-13
Loading

Data & Media loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error