f Cross-reaction of immune sera from patients with rickettsial diseases
- Authors: K. E. Hechemy, D. Raoult, J. Fox, Y. Han, L. B. Elliott, J. Rawlings
- First Published Online: 01 July 1989, Journal of Medical Microbiology 29: 199-202, doi: 10.1099/00222615-29-3-199
- Subject: Review Article
- Issue Published:
Rickettsia rickettsii and Rickettsia conorii are the causative agents of two common and serious diseases, Rocky Mountain spotted fever and Mediterranean spotted fever, respectively. In patients naturally infected with either of these organisms, antibodies are produced which cross-react with antigens of the other so extensively that diagnostic tests usually cannot identify the causative agents. The results of this study indicate that serodiagnostic tests with antigen from one of these two organisms could be used to detect antibodies in patients with either of the two rickettsial diseases.
© 1989 Pathological Society of Great Britain and Ireland | Published by the Microbiology Society
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