f Gardnerella vaginalis has a gram-positive cell-wall ultrastructure and lacks classical cell-wall lipopolysaccharide
- Authors: K. Sadhu, P. A. G. Domingue*, A. W. Chow, J. Nelligan, N. Cheng, J. W. Costerton
- *Correspondence should be sent to Dr P. A. G. Domingue.
- First Published Online: 01 July 1989, Journal of Medical Microbiology 29: 229-235, doi: 10.1099/00222615-29-3-229
- Subject: Review Article
- Issue Published:
Gardnerella vaginalis has a very thin cell wall with a characteristic gram-negative staining pattern and an apparent lamellar structure when viewed at an oblique angle by electronmicroscopy. Examination at right angles to the cell-wall plane and by freeze-etching showed absence of an outer membrane or any other lamellar structure. Cell-wall extracts made by methods specific for lipopolysaccharide (LPS) gave negative reactions by silver staining and for endotoxin in the limulus amoebocyte lysate assay. 2-Keto-3-deoxy-D-manno-2-octonoic acid (KDO), heptose and hydroxy fatty acids specific for LPS were not detected in the extracts. G. vaginalis cell walls are unequivocally gram-positive in their ultrastructural characteristics and chemical composition.
© 1989 Pathological Society of Great Britain and Ireland | Published by the Microbiology Society
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