1887

Abstract

Summary

The interaction of purified from rat lungs with rat peritoneal macrophages and human circulating polymorphonuclear leucocytes was studied by amplified chemiluminescence and examination of stained cytospin preparations. A polyclonal rat antiserum to was opsonic with both types of phagocyte. Complement had no opsonic properties alone but produced a synergic effect in combination with antibody.

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1992-04-01
2024-04-28
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References

  1. Frenkel J. K., Bartlett M. S., Smith J. W. RNA homology and the reclassification of Pneumocystis. Diagn Microbiol Infect Dis 1990; 13:1–2
    [Google Scholar]
  2. Matsumoto Y., Yoshida Y. Advances in Pneumocystis biology. Parasitology Today 1986; 2:137–142
    [Google Scholar]
  3. Hughes W. T. Pneumocystis carinii pneumonitis. Boca Raton CRC Press Inc 1987
    [Google Scholar]
  4. Burns S. M., Read J. A., Yap P. L., Brettle R. P. Reduced concentrations of IgG antibodies to Pneumocystis carinii in HIV-infected patients during active Pneumocystis carinii infection and the possibility of passive immunisation. J Infect 1990; 20:33–39
    [Google Scholar]
  5. Pesanti E. L. Effects of bacterial pneumonitis on development of pneumocystosis in rats. Am Rev Respir Dis 1982; 125:723–726
    [Google Scholar]
  6. Telzac E. E., Cote R. J., Gold J. W. M., Campbell S. W., Armstrong D. Extrapulmonary Pneumocystis carinii infections. Rev Infect Dis 1990; 12:380–386
    [Google Scholar]
  7. Masur H. Interactions between Pneumocystis carinii and phagocytic cells. In Young L. S. (ed) Pneumocystis carinii pneumonia. Lung Biology in Health and Disease vol 22 New York: Marcel Dekker; 198477–95
    [Google Scholar]
  8. Mason G. R., Hashimoto C. H., Dickman P. S., Foutty L. F., Cobb C. J. Prognostic implications of bronchoalveolar lavage neutrophilia in patients with Pneumocystic carinii pneumonia and AIDS. Am Rev Respir Dis 1989; 139:1336–1342
    [Google Scholar]
  9. Kaner R. J., St Mason G. R., Hashimoto C. H., Dickman P. S., Foutty L. F., Cobb C. J. Prognostic implications of bronchoalveolar lavage neutrophilia in patients with Pneumocystic carinii pneumonia and AIDS. Am Rev Respir Dis 1989; 139:1336–1342
    [Google Scholar]
  10. Von Behren L. A., Pesanti E. L. Uptake and degradation of Pneumocystic carinii by macrophages in vitro. Am Rev Respir Dis 1978; 118:1051–1059
    [Google Scholar]
  11. Masur H., Jones T. C. The interaction in vitro of Pneumocystis carinii with macrophages and L-cells. J Exp Med 1978; 147:157–170
    [Google Scholar]
  12. Pesanti E. L. In vitro effects of antiprotozoan drugs and immune serum on Pneumocystis carinii. J Infect Dis 1980; 141:775–780
    [Google Scholar]
  13. Hendley J. O., Weller T. H. Activation and transmission in rats of infection with Pneumocystis. Proc Soc Exp Biol Med 1971; 137:1401–1404
    [Google Scholar]
  14. Taylor M. B., Easmon C. S. F. Separation of Pneumocystis carinii from the lung of the steroid-suppressed rat. FEMS Microbiol Lett 1990; 70:49–54
    [Google Scholar]
  15. Allen R. C. Lucigenin chemiluminescence: a new approach to the study of polymorphonuclear leukocyte redox activity. In DeLuca M. A., McElroy W. D. (eds) Bioluminescence and chemiluminescence New York: Academic Press; 198163–73
    [Google Scholar]
  16. Stevens P., Welch W. D. Measurement of opsonic activity of serum by granulocyte chemiluminescence. In DeLuca M. A. McElroy (eds) Bioluminescence and chemiluminescence New York: Academic Press; 198175–80
    [Google Scholar]
  17. Jackson P. R., Pappas M. G., Hansen B. D. Fluorogenic substrate detection of viable intracellular and extracellular pathogenic protozoa. Science 1985; 227:435–438
    [Google Scholar]
  18. Blake D. R., Allen R. E., Lunec J. Free radicals in biological systems—a review orientated to inflammatory processes. Br Med Bull 1987; 43:371–385
    [Google Scholar]
  19. Allen R. C., Stjemholm R. L., Steele R. H. Evidence for the generation of an electronic excitation state(s) in human polymorphonuclear leukocytes and its participation in bactericidal activity. Biochem Biophys Res Commun 1972; 47:679–684
    [Google Scholar]
  20. Waltzer P. D., Cushion M. T. Immunobiology of Pneumocystis carinii. Pathol Immunopathol Res 1989; 8:127–140
    [Google Scholar]
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