f Phosphorylcholine-containing antigens in bacteria from the mouth and respiratory tract
- Authors: S. H. Gillespie*, S. Ainscough, A. Dickens, J. Lewin
- *Corresponding author: S. H. Gillespie.
- J. Med. Microbiol., January 1996 44: 35-40, doi: 10.1099/00222615-44-1-35
- Subject: Oral Microbiology
- Published Online:
Phosphorylcholine (PC)-containing antigens were sought in 269 bacterial isolates from the mouth and respiratory tract by an enzyme immunoassay method. Only 41 (15%) isolates were PC-positive and of these 29 (70%) were strains of Haemophilus influenzae. Other species that produced positive results included two of five isolates of Gemella haemolysans, two of five isolates of Micrococcus spp., and a single strain each of Bacillus sp., Corynebacterium jeikeium, Lactococcus sp. and H. parainfluenzae. The presence of PC-containing antigens in H. influenzae may be an important source of cross-reaction in antigen detection techniques that detect the C-polysaccharide antigen of Streptococcus pneumoniae in respiratory specimens and would result in false positive results.
© 1996 The Pathological Society of Great Britain and Ireland | Published by the Microbiology Society
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