1887

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Volume 65, Issue 10

Prevalence of colonization in autopsy cases in Turkey Free

Abstract

Detection of and its DNA in clinically asymptomatic people is defined as colonization. The aim of this study was to reveal the colonization prevalence of and affecting factors in an immunocompetent population. The study included 200 cases undergoing forensic autopsy between February 2015 and April 2015. The cause of death was non-medical conditions (group 1) in 111 cases (55.5 %), medical conditions (group 2) in 73 cases (36.5 %) and undetermined (group 3) in 16 cases (group 3). Tissue specimens about 1 g in weight were taken from the right upper pulmonary lobe. After DNA extraction, nested PCR targeting mitochondrial large subunit rRNA was used to detect . Of 200 cases, 37 (18.5 %) had DNA. There was not a significant difference in place of living, gender, smoking status and medication use between the cases with and those without . A significantly high rate of colonization was detected in group 2 (²=7.674; =0.022). -colonized cases also had a chronic disease in 2 of 13 (group 1), 12 of 20 (group 2) and 1 of 4 (group 3) cases (²=5.571; =0.062). A significantly high rate of the cases aged 0–1 year had (5/11; 45.5 %) (²=5.639; =0.018). The results of the study suggest that infants and patients with chronic diseases like cardiac or pulmonary diseases can be at risk for colonization.

  • Received:
  • Accepted:
  • Published Online:
Keyword(s): autopsy , colonization , P. jirovecii and prevalence
© 2016 The Authors
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2016-10-18
2024-04-20
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Prevalence of Pneumocystis jirovecii colonization in autopsy cases in Turkey
J. Med. Microbiol. 65, 1152 (2016); https://doi.org/10.1099/jmm.0.000337
/content/journal/jmm/10.1099/jmm.0.000337
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