Occurrence and characterization of extended-spectrum cephalosporin-resistant Enterobacteriaceae in healthy household dogs in Greece Liakopoulos, Apostolos and Betts, Jonathan and La Ragione, Roberto and van Essen-Zandbergen, Alieda and Ceccarelli, Daniela and Petinaki, Efthymia and Koutinas, Christos K. and Mevius, Dik J.,, 67, 931-935 (2018), doi = https://doi.org/10.1099/jmm.0.000768, publicationName = Microbiology Society, issn = 0022-2615, abstract= Extended-spectrum cephalosporin- and/or carbapenem-resistant (ESCR and/or CarbR) Enterobacteriaceae constitute a public health hazard because of limited treatment options and are endemic among humans in Greece. Recently, ESCR and CarbR Enterobacteriaceae have been increasingly isolated from companion animals, stressing their potential role as a reservoir for humans. However, the presence of ESCR bacteria in companion animals within Greek households has not been determined yet. Genes conferring the ESCR and CarbR phenotype were detected among canine isolates and their chromosomal or plasmid location was determined. Standard methods were applied for plasmid characterization. The clonal relatedness of the recovered isolates was examined by multilocus sequence typing (MLST). Here, we report the first findings on the presence of ESCR Enterobacteriaceae in healthy Greek dogs. ESCR Escherichia coli isolates were associated with different sequence types (STs), including the human pandemic ST131 clone. The occurrence of human-related ESBL/pAmpC genes, plasmid types and/or strain STS in this animal reservoir suggests possible bilateral transmission., language=, type=