1887

Abstract

Mycoplasma amphoriforme is a species closely related to Mycoplasma pneumoniae, thus far with unknown clinical impact. The application of optimized diagnostics, better capable of differentiating between these two micro-organisms, identified a significant patient population positive for M. amphoriforme. The PCR designed by Ling et al. was used on respiratory samples that originally tested positive for M. pneumoniae (n=78), and identified 29 retrospectively as M. amphoriforme. The aim of this study is to describe and compare both groups. The group infected with M. amphoriforme was significantly older and more frequently had a co-infection (19 % vs 62 %), COPD and less fever. This could suggest that M. amphoriforme has opportunistic characteristics.

Keyword(s): amphoriforme , Mycoplasma and pneumoniae
Loading

Article metrics loading...

/content/journal/jmm/10.1099/jmm.0.000809
2018-07-27
2024-04-19
Loading full text...

Full text loading...

/deliver/fulltext/jmm/67/9/1348.html?itemId=/content/journal/jmm/10.1099/jmm.0.000809&mimeType=html&fmt=ahah

References

  1. Webster D, Windsor H, Ling C, Windsor D, Pitcher D. Chronic bronchitis in immunocompromised patients: association with a novel Mycoplasma species. Eur J Clin Microbiol Infect Dis 2003; 22:530–534 [View Article][PubMed]
    [Google Scholar]
  2. Gillespie SH, Ling CL, Oravcova K, Pinheiro M, Wells L et al. Genomic investigations unmask Mycoplasma amphoriforme, a new respiratory pathogen. Clin Infect Dis 2015; 60:381–388 [View Article][PubMed]
    [Google Scholar]
  3. Ling CL, Oravcova K, Beattie TF, Creer DD, Dilworth P et al. Tools for detection of Mycoplasma amphoriforme: a primary respiratory pathogen?. J Clin Microbiol 2014; 52:1177–1181 [View Article][PubMed]
    [Google Scholar]
  4. Pereyre S, Renaudin H, Touati A, Charron A, Peuchant O et al. Detection and susceptibility testing of Mycoplasma amphoriforme isolates from patients with respiratory tract infections. Clin Microbiol Infect 2010; 16:1007–1009 [View Article][PubMed]
    [Google Scholar]
  5. Pitcher DG, Windsor D, Windsor H, Bradbury JM, Yavari C et al. Mycoplasma amphoriforme sp. nov., isolated from a patient with chronic bronchopneumonia. Int J Syst Evol Microbiol 2005; 55:2589–2594 [View Article][PubMed]
    [Google Scholar]
  6. Katsukawa C, Asai S, Mizutani K, Arai K, Kohdera U et al. Novel isolation of Mycoplasma amphoriforme from a pediatric patient with protracted bronchitis in Japan. Jpn J Infect Dis 2016; 69:450–451 [View Article][PubMed]
    [Google Scholar]
  7. Sánchez-Vargas FM, Gómez-Duarte OG. Mycoplasma pneumoniae-an emerging extra-pulmonary pathogen. Clin Microbiol Infect 2008; 14:105–115 [View Article][PubMed]
    [Google Scholar]
  8. Tjhie JH, van Kuppeveld FJ, Roosendaal R, Melchers WJ, Gordijn R et al. Direct PCR enables detection of Mycoplasma pneumoniae in patients with respiratory tract infections. J Clin Microbiol 1994; 32:11–16[PubMed]
    [Google Scholar]
  9. Hardegger D, Nadal D, Bossart W, Altwegg M, Dutly F. Rapid detection of Mycoplasma pneumoniae in clinical samples by real-time PCR. J Microbiol Methods 2000; 41:45–51 [View Article][PubMed]
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jmm/10.1099/jmm.0.000809
Loading
/content/journal/jmm/10.1099/jmm.0.000809
Loading

Data & Media loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error