%0 Journal Article %A Uechi, Kohei %A Tada, Tatsuya %A Sawachi, Yusuke %A Hishinuma, Tomomi %A Takaesu, Rei %A Nakama, Mika %A Nakasone, Isamu %A Kirikae, Teruo %A Fujita, Jiro %T A carbapenem-resistant clinical isolate of Aeromonas hydrophila in Japan harbouring an acquired gene encoding GES-24 β-lactamase %D 2018 %J Journal of Medical Microbiology, %V 67 %N 11 %P 1535-1537 %@ 1473-5644 %R https://doi.org/10.1099/jmm.0.000842 %K Aeromonas hydrophila %K carbapenem-resistant %K carbapenemase %K GES-24 %I Microbiology Society, %X Several species of Aeromonas produce the enzyme CphA metallo-β-lactamase. This study describes an isolate of Aeromonas hydrophila harbouring an acquired gene encoding the carbapenemase GES-24. This isolate was obtained from an inpatient in Okinawa, Japan, with no apparent record of travelling overseas. The minimum inhibitory concentrations of carbapenems against this isolate were 8 µg ml−1 for imipenem and 16 µg ml−1 for meropenem. Recombinant GES-24 hydrolyzed all of the tested β-lactams, including imipenem and meropenem. The genomic environment surrounding bla GES-24 was intI1-bla GES-24 -aac(6′)-IIc-qacEdelta1-sulI-orfX-tetR-tetE. This is the first report of A. hydrophila producing a GES-type carbapenemase. %U https://www.microbiologyresearch.org/content/journal/jmm/10.1099/jmm.0.000842