RT Journal Article SR Electronic(1) A1 Uechi, Kohei A1 Tada, Tatsuya A1 Sawachi, Yusuke A1 Hishinuma, Tomomi A1 Takaesu, Rei A1 Nakama, Mika A1 Nakasone, Isamu A1 Kirikae, Teruo A1 Fujita, JiroYR 2018 T1 A carbapenem-resistant clinical isolate of Aeromonas hydrophila in Japan harbouring an acquired gene encoding GES-24 β-lactamase JF Journal of Medical Microbiology, VO 67 IS 11 SP 1535 OP 1537 DO https://doi.org/10.1099/jmm.0.000842 PB Microbiology Society, SN 1473-5644, AB Several species of Aeromonas produce the enzyme CphA metallo-β-lactamase. This study describes an isolate of Aeromonas hydrophila harbouring an acquired gene encoding the carbapenemase GES-24. This isolate was obtained from an inpatient in Okinawa, Japan, with no apparent record of travelling overseas. The minimum inhibitory concentrations of carbapenems against this isolate were 8 µg ml−1 for imipenem and 16 µg ml−1 for meropenem. Recombinant GES-24 hydrolyzed all of the tested β-lactams, including imipenem and meropenem. The genomic environment surrounding bla GES-24 was intI1-bla GES-24 -aac(6′)-IIc-qacEdelta1-sulI-orfX-tetR-tetE. This is the first report of A. hydrophila producing a GES-type carbapenemase., UL https://www.microbiologyresearch.org/content/journal/jmm/10.1099/jmm.0.000842