1887

Abstract

The distribution of different serovars in Hungary has not been reported previously. The objective of this study was to determine the distribution and prevalence of serovars in a high-risk population by genotyping. The endocervical specimens of 484 female sex workers (FSWs) were screened for by plasmid PCR. Genotyping was performed in all -positive samples by PCR-based RFLP analysis of the gene. A total of 32 specimens (6.6 %) were positive for . Age was an important risk factor for infection in FSWs. The highest prevalence was detected in women under the age of 20 (18.8 %). All positive specimens were successfully genotyped and seven serovars were identified. The most prevalent was serovar D (34.4 %), followed by E (21.9 %), F (18.8 %), G (9.4 %), J (9.4 %), H (3.1 %) and I (3.1 %). A heterogeneous distribution of serovars was observed in the study group, where the most common serovars were D, E and F comprising 75 % of the positive samples. This PCR-based RFLP method could be used in epidemiological studies on the prevalence of infection to provide more information and to compare the serovar distribution among different cohorts.

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2009-06-01
2024-03-28
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