@article{mbs:/content/journal/jmm/10.1099/jmm.0.015925-0, author = "Amir, N. H. and Rossney, A. S. and Veale, J. and O'Connor, M. and Fitzpatrick, F. and Humphreys, H.", title = "Spread of community-acquired meticillin-resistant Staphylococcusaureus skin and soft-tissue infection within a family: implications forantibiotic therapy and prevention", journal= "Journal of Medical Microbiology", year = "2010", volume = "59", number = "4", pages = "489-492", doi = "https://doi.org/10.1099/jmm.0.015925-0", url = "https://www.microbiologyresearch.org/content/journal/jmm/10.1099/jmm.0.015925-0", publisher = "Microbiology Society", issn = "1473-5644", type = "Journal Article", keywords = "PVL, Panton–Valentineleukocidin", keywords = "CA-MRSA, community-acquired meticillin-resistant Staphylococcus aureus", keywords = "MLST, multilocus sequence type", keywords = "SCCmec, staphylococcal cassette chromosome mec", keywords = "SSTI, skin and soft-tissue infection", keywords = "HA-MRSA, healthcare-associated MRSA", abstract = "Outbreaks or clusters of community-acquired meticillin-resistant Staphylococcusaureus (CA-MRSA) within families have been reported. We describea family cluster of CA-MRSA skin and soft-tissue infection where CA-MRSA wassuspected because of recurrent infections which failed to respond to flucloxacillin.While the prevalence of CA-MRSA is low worldwide, CA-MRSA should be consideredin certain circumstances depending on clinical presentation and risk assessment.Surveillance cultures of family contacts of patients with MRSA should be consideredto help establish the prevalence of CA-MRSA and to inform the optimal choiceof empiric antibiotic treatment.", }