%0 Journal Article %A Amir, N. H. %A Rossney, A. S. %A Veale, J. %A O'Connor, M. %A Fitzpatrick, F. %A Humphreys, H. %T Spread of community-acquired meticillin-resistant Staphylococcusaureus skin and soft-tissue infection within a family: implications forantibiotic therapy and prevention %D 2010 %J Journal of Medical Microbiology, %V 59 %N 4 %P 489-492 %@ 1473-5644 %R https://doi.org/10.1099/jmm.0.015925-0 %K PVL, Panton–Valentineleukocidin %K CA-MRSA, community-acquired meticillin-resistant Staphylococcus aureus %K MLST, multilocus sequence type %K SCCmec, staphylococcal cassette chromosome mec %K SSTI, skin and soft-tissue infection %K HA-MRSA, healthcare-associated MRSA %I Microbiology Society, %X Outbreaks or clusters of community-acquired meticillin-resistant Staphylococcusaureus (CA-MRSA) within families have been reported. We describea family cluster of CA-MRSA skin and soft-tissue infection where CA-MRSA wassuspected because of recurrent infections which failed to respond to flucloxacillin.While the prevalence of CA-MRSA is low worldwide, CA-MRSA should be consideredin certain circumstances depending on clinical presentation and risk assessment.Surveillance cultures of family contacts of patients with MRSA should be consideredto help establish the prevalence of CA-MRSA and to inform the optimal choiceof empiric antibiotic treatment. %U https://www.microbiologyresearch.org/content/journal/jmm/10.1099/jmm.0.015925-0