1887

Abstract

Two studies of meningococcal carriage state were carried out in Galicia (Spain) before and after a mass vaccination campaign between December 1996 and January 1997 against serogroup C with meningococcal serogroups A and C polysaccharide vaccine. The studies covered two areas with different incidence rates of meningococcal disease in 1996 (high and low incidence). Carriage rates of serogroup C showed a decrease in both areas, 47 and 65 % respectively, before and after the vaccination. Results showed a decrease in carrier state in the age groups 10–14- and 15–19-year-olds, but not in the 5–9-year-olds. These results demonstrate the effect of immunization on the reduction of the carriage state.

Loading

Article metrics loading...

/content/journal/jmm/10.1099/jmm.0.04927-0
2003-01-01
2024-03-28
Loading full text...

Full text loading...

/deliver/fulltext/jmm/52/1/75.html?itemId=/content/journal/jmm/10.1099/jmm.0.04927-0&mimeType=html&fmt=ahah

References

  1. Broome C. V. 1986; The carrier state: Neisseria meningitidis . J Antimicrob Chemother 18:Suppl25–34
    [Google Scholar]
  2. Di Martino M, Cali G, Astorre P, Usai G. C, Ferrari R, Stroffolini T. 1990; Meningococcal carriage and vaccination in army recruits in Italy. Boll Ist Sieroter Milan 69:357–359
    [Google Scholar]
  3. Dirección Xeral de Saúde Pública 1995; A enfermidade meningocócica en Galicia. Bol Epidemiol Galicia 8:1–2
    [Google Scholar]
  4. Dirección Xeral de Saúde Pública 1998; A enfermidade meningocócica en Galicia trala campaña de vacinación. Bol Epidemiol Galicia 11:1–2
    [Google Scholar]
  5. Fernández S, Arreaza L, Santiago I, Malvar A, Berron S, Vazquez J. A, Hervada X, Gestal J. J. 1999; Carriage of a new epidemic strain of Neisseria meningitidis and its relationship with the incidence of meningococcal disease in Galicia, Spain. Epidemiol Infect 123:349–357 [CrossRef]
    [Google Scholar]
  6. Gotschlich E. C, Goldschneider I, Artenstein M. S. 1969; Human immunity to the meningococcus, V. The effect of immunization on the carrier state. J Exp Med 129:1385–1394 [CrossRef]
    [Google Scholar]
  7. Neal K. R, Irwin D. J, Davies S, Kaczmarski E. B, Wale M. C. J. 1998; Sustained reduction in the carriage of Neisseria meningitidis as a result of a community meningococcal disease control programme. Epidemiol Infect 121:487–493 [CrossRef]
    [Google Scholar]
  8. Stroffolini T, Angelini L, Galanti I, Occhionero M, Congiu M. E, Mastrantonio P. 1990; The effect of meningococcal group A and C polysaccharide vaccine on nasopharyngeal carrier state. Microbiologica 13:225–229
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jmm/10.1099/jmm.0.04927-0
Loading
/content/journal/jmm/10.1099/jmm.0.04927-0
Loading

Data & Media loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error