1887

Abstract

has been reported as an increasingly frequent cause of localized and disseminated infections in immunocompromised patients in recent years, but bacteraemia remains a rare finding. Here, the case is described of a 68-year-old man with end-stage renal disease and idiopathic thrombocytopenia purpura treated with steroid therapy who developed disseminated infection (bacteraemia, multilobar pneumonia and brain abscesses) due to . The isolate was confirmed by partial sequencing analysis of the 16S rRNA gene. The patient recovered after prolonged trimethoprim-sulfamethoxazole therapy with no recurrence in over 1 year.

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2005-11-01
2024-03-28
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References

  1. Beaman B. L., Beaman L. 1994; Nocardia species: host-parasite relationships. Clin Microbiol Rev 7:213–264
    [Google Scholar]
  2. Bhave A. A., Thirunavukkarasu K., Gottlieb D. J., Bradstock K. 1999; Disseminated nocardiosis in a bone marrow transplant recipient with chronic GVHD. Bone Marrow Transplant 23:519–521 [CrossRef]
    [Google Scholar]
  3. Boiron P., Provost F., Chevrier G., Dupont B. 1992; Review of nocardial infections in France from 1987 to 1990. Eur J Clin Microbiol Infect Dis 11:709–714 [CrossRef]
    [Google Scholar]
  4. Brown J. M., McNeil M. 2003; Nocardia , Rhodococcus , Gordonia , Actinomyces , Streptomyces , and other aerobic actinomycetes. In Manual of Clinical Microbiology , 8th edn. pp 502–531 Edited by Murray P. R. and others Washington, DC: American Society for Microbiology;
    [Google Scholar]
  5. Christidou A., Maraki S., Scoulica E., Mantadakis E., Agelaki S., Samonis G. 2004; Fatal Nocardia farcinica bacteremia in a patient with lung cancer. Diagn Microbiol Infect Dis 50:135–149 [CrossRef]
    [Google Scholar]
  6. Ertl G., Schaal K. P., Kochsieck K. 1987; Nocardial endocarditis of an aortic valve prosthesis. Br Heart J 57:384–386 [CrossRef]
    [Google Scholar]
  7. Farina C., Boiron P., Goglio A., Provost F. 1995; Human nocardiosis in northern Italy from 1982 to 1992.Northern Italy collaborative group on nocardiosis. Scand J Infect Dis 27:23–27 [CrossRef]
    [Google Scholar]
  8. Farina C., Boiron P., Ferrai I., Provost F., Goglio A. 2001; Report of human nocardiosis in Italy between 1993 and 1997. Eur J Epidemiol 17:1019–1022 [CrossRef]
    [Google Scholar]
  9. Hitti W., Wolff M. 2005; Two cases of multidrug-resistant Nocardia farcinica infection in immunosuppressed patients and implications for empiric therapy. Eur J Clin Microbiol Infect Dis 24:142–144 [CrossRef]
    [Google Scholar]
  10. Kontoyiannis D. P., Ruoff K., Hooper D. C. 1998; Nocardia bacteremia.Report of four cases and review of the literature. Medicine 77:255–266 [CrossRef]
    [Google Scholar]
  11. Minamoto G. Y., Sordillo E. M. 1998; Disseminated nocardiosis in a patient with AIDS: diagnosis by blood culture and cerebrospinal fluid cultures. Clin Infect Dis 26:242–243 [CrossRef]
    [Google Scholar]
  12. National Committee for Clinical Laboratory Standards; 2000; Susceptibility Testing of Mycobacteria, Nocardia, and Other Aerobic Actinomycetes; Tentative Standard . , 2nd edn. publication M24-T2 Wayne, PA: National Committee for Clinical Laboratory Standards;
  13. Peters B. R., Saubolle M. A., Costantino J. M. 1996; Disseminated and cerebral infection due to Nocardia farcinica : diagnosis by blood culture and cure with antibiotics alone. Clin Infect Dis 23:1165–1167 [CrossRef]
    [Google Scholar]
  14. Torres O. H., Domingo P., Pericas R., Boiron P., Montiel J. A., Vazquez G. 2000; Infection caused by Nocardia farcinica : case report and review. Eur J Clin Microbiol Infect Dis 19:205–212 [CrossRef]
    [Google Scholar]
  15. Turenne C. Y., Tschetter L., Wolfe J., Kabani A. 2001; Necessity of quality-controlled 16S rRNA gene sequence databases: identifying nontuberculous Mycobacterium species. J Clin Microbiol 39:3637–3648 [CrossRef]
    [Google Scholar]
  16. Wallace R. J. Jr, Tsukamura M., Brown B. A., Brown J. M., Onyi G. O. 1990; Cefotaxime-resistant Nocardia asteroides strains are isolates of the controversial species Nocardia farcinica . J Clin Microbiol 28:2726–2732
    [Google Scholar]
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