1887

Abstract

Peritoneal dialysis-associated peritonitis due to fungi of the class occurs very rarely. A case of fungal continuous ambulatory peritoneal dialysis peritonitis due to is reported in a 39-year-old Aboriginal woman with end-stage renal failure and diabetes mellitus. This isolate was found to be resistant to amphotericin B, 5-fluorocytosine, fluconazole, itraconazole, ketoconazole and voriconazole. However, this patient was successfully treated with voriconazole and removal of the Tenckhoff dialysis catheter. Zygomycoses are an emerging threat among immunocompromised patients, including those with chronic renal failure. Zygomycosis due to is frequently fatal and is often non-responsive to systemic antifungal therapy. This is believed to be the first reported case of causing peritonitis in humans and one of the minority of cases involving this organism with a successful outcome.

Loading

Article metrics loading...

/content/journal/jmm/10.1099/jmm.0.46202-0
2006-01-01
2024-04-27
Loading full text...

Full text loading...

/deliver/fulltext/jmm/55/1/115.html?itemId=/content/journal/jmm/10.1099/jmm.0.46202-0&mimeType=html&fmt=ahah

References

  1. Bibashi E., Memmos D., Kokolina E., Tsakiris D., Sofianou D., Papadimitriou M. 2003; Fungal peritonitis complicating peritoneal dialysis during an 11-year period: report of 46 cases. Clin Infect Dis 36:927–931 [CrossRef]
    [Google Scholar]
  2. Dannaoui E., Afeltra J., Meis J. F., Verweij P. E., Eurofung Network. 2002; In vitro susceptibilities of zygomycetes to combinations of antimicrobial agents. Antimicrob Agents Chemother 46:2708–2711 [CrossRef]
    [Google Scholar]
  3. Dannaoui E., Meletiadis J., Mouton J. W., Meis J. F., Verweij P. E., Eurofung Network. 2003; In vitro susceptibilities of zygomycetes to conventional and new antifungals. J Antimicrob Chemother 51:45–52 [CrossRef]
    [Google Scholar]
  4. De Hoog G. S., Guarro J., Gené J., Figueras M. J. 2000 Atlas of Clinical Fungi , 2nd edn. Utrecht, Netherlands: Centraalbureau voor Schimmelcultures;
    [Google Scholar]
  5. Eisenberg E. S., Leviton I., Soeiro R. 1986; Fungal peritonitis in patients receiving peritoneal dialysis: experience with 11 patients and review of the literature. Rev Infect Dis 8:309–321 [CrossRef]
    [Google Scholar]
  6. Gloor H. J., Pandolfi S., Ruttimann S. 2003; 20 years of peritoneal dialysis in a mid-sized Swiss hospital. Swiss Med Wkly 133:619–624
    [Google Scholar]
  7. Kontoyianis D. P., Vartivarian S., Anaissie E. J., Samonis G., Bodey G. P., Rinaldi M. 1994; Infections due to Cunninghamella bertholletiae in patients with cancer: report of three cases and review. Clin Infect Dis 18:925–928 [CrossRef]
    [Google Scholar]
  8. Kontoyiannis D. P., Lionakis M. S., Lewis R. E. & 8 other authors; 2005; Zygomycosis in a tertiary-care cancer center in the era of Aspergillus -active antifungal therapy: a case-control observational study of 27 recent cases. J Infect Dis 191:1350–1360 [CrossRef]
    [Google Scholar]
  9. Mazade M. A., Margolin J. F., Rossmann S. N., Edwards M. S. 1998; Survival from pulmonary infection with Cunninghamella bertholletiae : case report and review of the literature. Pediatr Infect Dis J 17:835–839 [CrossRef]
    [Google Scholar]
  10. Nannini E. C., Paphitou N. I., Ostrosky-Zeichner L. 2003; Peritonitis due to Aspergillus and zygomycetes in patients undergoing peritoneal dialysis: report of 2 cases and review of the literature. Diagn Microbiol Infect Dis 46:49–54 [CrossRef]
    [Google Scholar]
  11. Ng T. T., Campbell C. K., Rothera M., Houghton J. B., Hughes D., Denning D. W. 1994; Successful treatment of sinusitis caused by Cunninghamella bertholletiae . Clin Infect Dis 19:313–316 [CrossRef]
    [Google Scholar]
  12. Quinio D., Karam A., Leroy J. P., Moal M. C., Bourbigot B., Masure O., Sassolas B., Le Flohic A. M. 2004; Zygomycosis caused by Cunninghamella bertholletiae in a kidney transplant recipient. Med Mycol 42:177–180 [CrossRef]
    [Google Scholar]
  13. Ribes J. A., Vanover-Sams C. L., Baker D. J. 2000; Zygomycetes in human disease. Clin Micro Rev 13:236–301 [CrossRef]
    [Google Scholar]
  14. Richardson M. D., Koukila-Kahkola P., Shankland G. S. 2003; Rhizopus , Rhizomucor , Absidia , and other agents of systemic and subcutaneous zygomycoses. In Manual of Clinical Microbiology , 8th edn. pp  1761–1780 Edited by Murray P. R. Washington, DC: American Society for Microbiology;
    [Google Scholar]
  15. Ritz N., Ammann R. A., Aebischer C. C., Gugger M., Jaton K., Schmid R. A., Aebi C. 2005; Failure of voriconazole to cure disseminated zygomycosis in an immunocompromised child. Eur J Pediatr 164:231–235 [CrossRef]
    [Google Scholar]
  16. Sun Q. N., Fothergill A. W., McCarthy D. I., Rinaldi M. G., Graybill J. R. 2002; In vitro activities of posaconazole, itraconazole, voriconazole, amphotericin B, and fluconazole against 37 clinical isolates of zygomycetes. Antimicrob Agents Chemother 46:1581–1582 [CrossRef]
    [Google Scholar]
  17. Zhang R., Zhang J. W., Szerlip H. M. 2002; Endocarditis and hemorrhagic stroke caused by Cunninghamella bertholletiae infection after kidney transplantation. Am J Kidney Dis 40:842–846 [CrossRef]
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jmm/10.1099/jmm.0.46202-0
Loading
/content/journal/jmm/10.1099/jmm.0.46202-0
Loading

Data & Media loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error