%0 Journal Article %A Mascarenhas, Joana D'Arc P. %A Leite, José Paulo G. %A Lima, Jackson C. %A Heinemann, Marcos B. %A Oliveira, Darleise S. %A Araújo, Irene T. %A Soares, Luana S. %A Gusmão, Rosa Helena P. %A Gabbay, Yvone B. %A Linhares, Alexandre C. %T Detection of a neonatal human rotavirus strain with VP4 and NSP4 genes of porcine origin %D 2007 %J Journal of Medical Microbiology, %V 56 %N 4 %P 524-532 %@ 1473-5644 %R https://doi.org/10.1099/jmm.0.46635-0 %K SG, subgroup %K EIA, enzyme immunoassay %K e-type, RNA electropherotype %I Microbiology Society, %X A human rotavirus strain (NB-150) was detected in stool samples from a neonate hospitalized for mild/moderate community-acquired diarrhoea. This baby lived in the outskirts of Belém, Brazil, under poor sanitation conditions. The NB-150 strain displayed a typical long electrophoretic pattern with 11 gene segments. It had two VP7 alleles, G1 and G4, and belonged to VP6 subgroup II. A close relatedness with human rotaviruses was shown for VP7 alleles: G1 (96.9–100 % similarity at the amino acid level) and G4 (97.1–100 % similarity at the amino acid level). As for VP6, 95.1–97.5 % similarity at the amino acid level was noted. VP8* and NSP4 genes showed a close relatedness with those of porcine rotavirus strains, as follows: VP8* (95.0 % similarity at the amino acid level) and NSP4 (93.7–96.0 % similarity at the amino acid level). This is believed to be the first report in Brazil of a rotavirus infection involving a strain with G1 and G4 alleles, with VP8* and NSP4 genes of porcine origin. These findings strongly suggest the occurrence of interspecies transmission. %U https://www.microbiologyresearch.org/content/journal/jmm/10.1099/jmm.0.46635-0