@article{mbs:/content/journal/jmm/10.1099/jmm.0.46692-0, author = "Heddema, Edou R. and van Hannen, Erik J. and Duim, Birgitta and de Jongh, Bartelt M. and Kaan, Jan A. and van Kessel, Rob and Lumeij, Johannes T. and Visser, Caroline E. and Vandenbroucke-Grauls, Christina M. J. E.", title = "An outbreak of psittacosis due to Chlamydophila psittaci genotype A in a veterinary teaching hospital", journal= "Journal of Medical Microbiology", year = "2006", volume = "55", number = "11", pages = "1571-1575", doi = "https://doi.org/10.1099/jmm.0.46692-0", url = "https://www.microbiologyresearch.org/content/journal/jmm/10.1099/jmm.0.46692-0", publisher = "Microbiology Society", issn = "1473-5644", type = "Journal Article", keywords = "CFT, complement fixation test", keywords = "MIF, microimmunofluorescence", keywords = "rELISA, recombinant ELISA", keywords = "IC, internal control", abstract = "An outbreak of psittacosis in a veterinary teaching hospital was recognized in December 2004. Outbreak management was instituted to evaluate the extent of the outbreak and to determine the avian source. Real-time PCR, serologic testing and sequencing of the ompA gene of Chlamydophila psittaci were performed. Sputum samples from patients, throat-swab samples from exposed students and staff, and faecal specimens from parrots and pigeons were tested. In this outbreak, 34 % (10/29) of the tested individuals were infected. The clinical features of the infection ranged from none to sepsis with multi-organ failure requiring intensive-care-unit admission. C. psittaci genotype A was identified as the outbreak strain. Parrots, recently exposed to a group of cockatiels coming from outside the teaching facility, which were used in a practical class, appeared to be the source of the outbreak. One of the tested pigeons harboured an unrelated C. psittaci genotype B strain. The microbiological diagnosis by real-time PCR on clinical specimens allowed for rapid outbreak management; subsequent genotyping of the isolates identified the avian source. Recommendations are made to reduce the incidence and extent of future outbreaks.", }