1887

Abstract

Summary

Oral candidal infection and the carriage of oral bacteria in rats has been studied in animals on a high carbohydrate diet and treated with tetracycline. Candidal infection was not significantly enhanced by carbohydrate alone but was promoted by tetracycline; carbohydrate plus tetracycline was no more effective than tetracycline alone. Carriage of lactobacilli was enhanced by carbohydrate but streptococcal carriage was depressed; there was no effect on the number of rats carrying enterobacteria. Administration of tetracycline reduced the carriage of all three groups of bacteria but the isolation rate for enterobacteria increased towards the end of the experiment, becoming nearly the same as at the start. The prevalence of did not vary with these changes in bacterial populations.

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1985-12-01
2024-04-24
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References

  1. Balish E., Phillips A. W. 1966; Growth and virulence of Candida albicans after oral inoculation in the chick with a monoflora of either Escherichia coli or Streptococcus faecalis. Journal of Bacteriology 91:1744–1749
    [Google Scholar]
  2. Bowen W. H., Cornick D. E. 1970; The microbiology of gingival-dental plaque. Recent findings from primate research. International Dental Journal 20:382–395
    [Google Scholar]
  3. Cormane R. H., Goslings W. R. O. 1963; Factors influencing the growth of Candida albicans (in-vivo and in-vitro studies). Sabouraudia 3:52–63
    [Google Scholar]
  4. Cowan S. T. 1974 Cowan and Steel’s manual for the identification of medical bacteria. , 2nd edn.. Cambridge University Press; Cambridge:
    [Google Scholar]
  5. Fisker A. V., Schiott C. R., Phillipsen H. P. 1982; Long-term oral candidosis in rats. Acta Pathologica Microbiologica Immunologica Scandinavica Section B 90:221–227
    [Google Scholar]
  6. Hassan O., Russell C. 1983; The effect of oral bacteria on the germination of Candida albicans. Journal of Dental Research 62:430 Abst. 136
    [Google Scholar]
  7. Isenberg H. D., Pisano M. A., Carito S. L., Berkman J. I. 1960; Factors leading to overt monilial disease. I. Preliminary studies of the ecological relationship between Candida albicans and intestinal bacteria. Antibiotics and Chemotherapy 10:353–363
    [Google Scholar]
  8. Jones J. H., Russell C. 1973; The histology of chronic candidal infection of the rat’s tongue and its relevance to human oral leukoplakia. Journal of Clinical Pathology 26:390
    [Google Scholar]
  9. Jones J. H., Russell C., Young C., Owen D. 1976; Tetracycline and the colonisation and infection of the mouths of germ-free and conventionalised rats with Candida albicans. Journal of Antimicrobial Chemotherapy 2:247–253
    [Google Scholar]
  10. Knight L., Fletcher J. 1971; Growth of Candida albicans in saliva: Stimulation by glucose associated with antibiotics, corticosteroids and diabetes mellitus. Journal of Infectious Diseases 123:371–377
    [Google Scholar]
  11. Olsen I., Birkeland J. M. 1976; Initiation and aggravation of denture stomatitis by sucrose rinses. Scandinavian Journal of Dental Research 84:94–97
    [Google Scholar]
  12. Russell C., Jones J. H. 1973a; The effects of oral inoculation of the yeast and mycelial phases of Candida albicans in rats fed on normal and carbohydrate-rich diets. Archives of Oral Biology 18:409–412
    [Google Scholar]
  13. Russell C., Jones J. H. 1973b; Effects of oral inoculation of Candida albicans in tetracycline-treated rats. Journal of Medical Microbiology 6:275–279
    [Google Scholar]
  14. Russell C., Jones J. H. 1975; The histology of prolonged candidal infection of the rat’s tongue. Journal of Oral Pathology 4:330–339
    [Google Scholar]
  15. Samaranayake L. P., MacFarlane T. W. 1980; An in-vitro study of the adherence of Candida albicans to acrylic surfaces. Archives of Oral Biology 25:603–609
    [Google Scholar]
  16. Samaranayake L. P., MacFarlane T. W. 1982; The effect of dietary carbohydrates on the in-vitro adhesion of Candida albicans to epithelial cells. Journal of Medical Microbiology 15:511–517
    [Google Scholar]
  17. Seelig M. S. 1966a; Role of antibiotics in the pathogenesis of Candida infections. American Journal of Medicine 40:887–917
    [Google Scholar]
  18. Seelig M. S. 1966b; Mechanisms by which antibiotics increase the incidence and severity of candidiasis and alter the immunological defenses. Bacteriological Reviews 30:442–459
    [Google Scholar]
  19. Siegel S. 1956 Nonparametric statistics for the behavioural sciences.. McGraw-Hill; New York:
    [Google Scholar]
  20. Taschdjian C. L., Burchall J. J., Kozinn P. J. 1960; Rapid identification of Candida albicans by filamentation on serum and serum substitutes. American Journal of Diseases of Children 99:212–215
    [Google Scholar]
  21. Young G., Krasner R. I., Yudkofsky P. L. 1956; Interactions of oral strains of Candida albicans and lactobacilli. Journal of Bacteriology 72:525–529
    [Google Scholar]
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