1887

Abstract

Summary

The increase in the number of cases of meningococcal disease reported to the Ministry of Health in Athens since 1989 prompted the present study to determine if isolates from patients or carriers expressed the same phenotypic characters as those in other parts of Europe. None of the isolates from patients (31) or carriers (547) expressed the antigenic combinations associated with outbreaks in northern Europe, i.e., B:15:P1.16 or B:4:P1.15. The majority of the Greek isolates did not react with any of the six monoclonal serotype reagents tested; however, most reacted with one or more of the 11 monoclonal subtype antibodies. The results suggest that additional serotype reagents are needed for epidemiological studies in southeastern Europe and that vaccines based on serotype antigens developed against outbreak strains in northern Europe would not be effective in Greece.

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1993-01-01
2024-04-20
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References

  1. Blackwell CC, Tzanakaki G, Kremastinou J. et al. Factors affecting carriage of Neisseria meningitidis among Greek military recruits. Epidemiol Infect 1992; 108:441–448
    [Google Scholar]
  2. Kalapothaki V, Vassilliadis P, Trichopoulos D, Kaklamam E. Sérié C. Caractéristiques séro-épidémiologiques chez les porteurs sains de Méningocoques en Grèce. Ann Micriobiol (Institut Pasteur) 1979; 130B:43–54
    [Google Scholar]
  3. Poolman JT, Jonsdottir K, Jones DM, Lind I, Froholm LO, Zanen HC. Meningococcal serotypes and serogroup B disease in North-West Europe. Lancet 1986; 2:555–558
    [Google Scholar]
  4. Poolman JT. Meningococcal vaccines. J Med Microbiol 1988; 26:170–172
    [Google Scholar]
  5. Ahdillahi H, Poolman JT. Typing of group-B Neisseria men ingitidis with monoclonal antibodies in whole-cell ELISA. J Med Microbiol 1988; 26:177–180
    [Google Scholar]
  6. Wedege E, Hoiby EA, Rosenqvist ER, Froholm LO. Serotyping and sublyping of Neisseria meningitidis isolates by coagglutination. dot-blotting and ELISA. J Med Microbiol 1990; 31:195–201
    [Google Scholar]
  7. Blackwell CC, Weir DM, James VS. et al. Secretor status. smoking and carriage of Neisseria meningitidis. Epidemiol Infect 1990; 104:203–209
    [Google Scholar]
  8. Blackwell CC, Tzanakaki G, Kremastinou J. et al. Carriage of Neisseria meningitidis among school children in Athens. Abstracts of the 120th Meeting of the Society for General Microbiology 1991
    [Google Scholar]
  9. Young H. Cultural diagnosis of gonorrhoea with modified New York City (MNYC) medium. Br J Vener Dis 1978; 54:36–40
    [Google Scholar]
  10. Young H, Paterson IC, McDonald DR. Rapid carbohydrate utilization test for identification of Neisseria gonorrhoeae. Br J Vener Dis 1976; 52:172–175
    [Google Scholar]
  11. Abdillahi H, Poolman JT. Whole-cell ELISA for typing Neisseria meningitidis with monoclonal antibodies. FEMS Microbiol Lett 1987; 48:367–371
    [Google Scholar]
  12. Fallon RJ. Meningococcal infections in Scotland 1990. Com municable Diseases and Environmental Health in Scotland Weekly Report 1991; 25:91/25.4–9
    [Google Scholar]
  13. Riou JY, Poolman JT, Auriol J, Lamprez F, Guibourdenche M. Serosubtyping of group B, C, Y and A meningococci isolated in France in 1988. Ann Biol Clin (Paris) 1989; 48:227–231
    [Google Scholar]
  14. Mastrantonio P, Congiu ME, Occhionero M, Stroffolini T. Genomic fingerprints and phenotypic characteristics of strains of Neisseria meningitidis causing disease in Italy. Microbiologica 1990; 13:109–113
    [Google Scholar]
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