1887

Journal of General Virology header logo

Volume 105, Issue 4

ICTV Virus Taxonomy Profile: 2024 Open Access

This article is part of the ICTV Virus Taxonomy Profiles collection.

Abstract

is a family for negative-sense RNA viruses with genomes of about 17.2–21.1 kb. These viruses are maintained in and/or transmitted by arthropods among birds, reptiles and mammals. Norwaviruses and orthonairoviruses can cause febrile illness in humans. Several orthonairoviruses can infect mammals, causing mild, severe and sometimes, fatal diseases. Nairovirids produce enveloped virions containing two or three single-stranded RNA segments with open reading frames that encode a nucleoprotein (N), sometimes a glycoprotein precursor (GPC), and a large (L) protein containing an RNA-directed RNA polymerase (RdRP) domain. This is a summary of the International Committee on Taxonomy of Viruses (ICTV) report on the family , which is available at www.ictv.global/report/nairoviridae.

  • Received:
  • Accepted:
  • Published Online:
Keyword(s): ICTV Report , nairovirid , Nairoviridae , nairovirus , orthonairovirus and taxonomy
Funding
This study was supported by the:
  • National Institute of Allergy and Infectious Diseases (Award HHSN272201800013C)
    • Principle Award Recipient: JensH. Kuhn
© 2024 The Authors
  • This is an open-access article distributed under the terms of the Creative Commons Attribution License.
Loading

Article metrics loading...

/content/journal/jgv/10.1099/jgv.0.001974
2024-04-30
2024-05-15
Loading full text...

Full text loading...

/deliver/fulltext/jgv/105/4/jgv001974.html?itemId=/content/journal/jgv/10.1099/jgv.0.001974&mimeType=html&fmt=ahah

References

  1. Garrison AR, Radoshitzky SR, Kota KP, Pegoraro G, Ruthel G et al. Crimean–Congo hemorrhagic fever virus utilizes a clathrin- and early endosome-dependent entry pathway. Virology 2013; 444:45–54 [View Article]
     [Google Scholar]
  2. Shtanko O, Nikitina RA, Altuntas CZ, Chepurnov AA, Davey RA. Crimean-Congo hemorrhagic fever virus entry into host cells occurs through the multivesicular body and requires ESCRT regulators. PLoS Pathog 2014; 10:e1004390 [View Article] [PubMed]
     [Google Scholar]
  3. Holm T, Kopicki J-D, Busch C, Olschewski S, Rosenthal M et al. Biochemical and structural studies reveal differences and commonalities among cap-snatching endonucleases from segmented negative-strand RNA viruses. J Biol Chem 2018; 293:19686–19698 [View Article] [PubMed]
     [Google Scholar]
  4. Bergeron É, Zivcec M, Chakrabarti AK, Nichol ST, Albariño CG et al. Recovery of recombinant Crimean Congo hemorrhagic fever virus reveals a function for non-structural glycoproteins cleavage by furin. PLoS Pathog 2015; 11:e1004879 [View Article] [PubMed]
     [Google Scholar]
  5. Booth TF, Gould EA, Nuttall PA. Structure and morphogenesis of Dugbe virus (Bunyaviridae, Nairovirus) studied by immunogold electron microscopy of ultrathin cryosections. Virus Res 1991; 21:199–212 [View Article] [PubMed]
     [Google Scholar]
  6. Rwambo PM, Shaw MK, Rurangirwa FR, DeMartini JC. Ultrastructural studies on the replication and morphogenesis of Nairobi sheep disease virus, a Nairovirus. Arch Virol 1996; 141:1479–1492 [View Article] [PubMed]
     [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jgv/10.1099/jgv.0.001974
Loading
ICTV Virus Taxonomy Profile: Nairoviridae 2024
J. Gen. Virol. 105, 001974 (2024); https://doi.org/10.1099/jgv.0.001974
/content/journal/jgv/10.1099/jgv.0.001974
/content/journal/jgv/10.1099/jgv.0.001974
Loading

Data & Media loading...

Most cited Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error