Clonal spread of an invasive strain of Haemophilus influenzae type b among nursery contacts accompanied by a high carriage rate of non-disease-associated strains
SAITO, MITSUMASA and OKADA, KENJI and TAKEMORI, KOUICHI and YOSHIDA, SHIN-ICHI,, 49, 845-847 (2000),
doi = https://doi.org/10.1099/0022-1317-49-9-845,
publicationName = Microbiology Society,
issn = 0022-2615,
abstract= Haemophilus influenza carriage was examined in unvaccinated nursery contacts of a patient with H. influenzae type b (Hib) meningitis and isolates were typed by pulsed-field gel electrophoresis (PFGE). Nasopharyngeal isolates were classified into eight PFGE patterns. Seven Hib carriers were found among 15 nursery contacts. The isolates from the carriers showed a PFGE pattern identical to that of the meningitis strain. The carrier rate of non-disease-associated strains was also high (47%, 7 of 15). This study suggests that the clonal spread of invasive (serotype b) H. influenzae strains is accompanied by a high carriage rate of non-disease-associated strains. ,
language=,
type=