Evidence that Leptospiral Lipopolysaccharide is not an Important Protective Antigen Adler, B. and Faine, S.,, 15, 259-262 (1982), doi = https://doi.org/10.1099/00222615-15-2-259, publicationName = Microbiology Society, issn = 0022-2615, abstract= SUMMARY CBA/N mice, which could not produce antibodies against lipopoly-saccharide (LPS) from either Escherichia coli or Leptospira interrogans serovar pomona, produced levels of agglutinating antibodies against leptospires similar to those produced by immunologically normal CBA mice. CBA/N mice were thus resistant to acute leptospiral infection and CBA/N immune serum passively protected immunosuppressed mice from infection. The results suggest that antibodies against LPS are not important in protection against experimental leptospiral infection in mice., language=, type=