Epidemiological data on Staphylococcus aureus strains producing synergohymenotropic toxins
Prevost, G. and Couppie, P. and Prevost, P. and Gayet, S. and Petiau, P. and Cribier, B. and Monteil, H. and Piemont, Y.,, 42, 237-245 (1995),
doi = https://doi.org/10.1099/00222615-42-4-237,
publicationName = Microbiology Society,
issn = 0022-2615,
abstract= Surmmary DNA hybridisation of 309 consecutive Staphylococcus aureus clinical isolates with oligonucleotide probes specific for genes encoding Panton-Valentine leucocidin (luk-PV) and y-haemolysin (hlg) revealed that 99% of randomly selected strains carried the hlg locus whereas only 2% harboured the luk-PV as well as the hlg loci. Only 1% of the strains did not possess either gene. In a clinical prospective study of independent S. aureus strains, 58 Panton-Valentine leucocidin (PVL)-producing isolates were shown to be responsible for primary skin infections, mainly furuncles (86 %). Phage susceptibility patterns and pulsed field gel electrophoresis (PFGE) profiles of DNA were shown to be polymorphic epidemiological markers of PVL-producing strains. In eight patients with recurrent furuncles, the PVL-producing strains isolated either from furuncles or from the anterior nares were considered to be identical in each based upon phage sensitivity profiles or PFGE patterns.,
language=,
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