Disseminated methicillin-susceptible Staphylococcus aureus infection

David R. Perkins; James A. Hall; Lisa M. Lopez; Lizbeth Janice Cahuayme-Zuniga

doi:10.1099/jmm.0.000644

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f Disseminated methicillin-susceptible Staphylococcus aureus infection

Authors: David R. Perkins¹ , James A. Hall^2,3 , Lisa M. Lopez^2,3 , Lizbeth Janice Cahuayme-Zuniga^2,3
- VIEW AFFILIATIONS
- ¹ 1St. George's University School of Medicine, St. George, Grenada ² 2Baylor Scott & White Memorial Hospital, Temple, TX, USA ³ 3Texas A&M Health Science Center College of Medicine, Temple, TX, USA
*Correspondence: James A. Hall [email protected]
First Published Online: 20 November 2017, Journal of Medical Microbiology 67: 83-86, doi: 10.1099/jmm.0.000644
Subject: Disease, Diagnosis and Diagnostics

Received: 22/09/2017
Accepted: 06/11/2017
Cover date: 01/01/2018

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Introduction. When clinicians think about Staphylococcus aureus bacteria, what comes to the mind of most is the dreaded methicillin-resistant form. However, clinicians should not forget the methicillin-susceptible type, which is just as virulent.

Case presentation. The authors present the case of a 20-year-old woman who was admitted with septic shock and multi-organ failure and was found to have disseminated methicillin-susceptible Staphylococcus aureus (MSSA) infection. The patient had persistent blood cultures positive for MSSA. A transesophageal echocardiogram showed a 1.1 cm vegetation in the mitral valve, and the patient had bilateral pleural effusions that grew MSSA. An MRI of the brain showed multiple areas consistent with infarctions thought to be secondary to septic emboli. The patient underwent a mitral valve replacement and was treated with a prolonged course of parenteral nafcillin.

Discussion. This case illustrates a severe clinical presentation and management of MSSA infections.

Keyword(s): multi-organ failure, septic shock, methicillin-susceptible Staphylococcus aureus infection

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