@article{mbs:/content/journal/jmm/10.1099/jmm.0.000885, author = "Kenyon, Chris", title = "Prevalence of macrolide resistance in Treponema pallidum is associated with macrolide consumption", journal= "Journal of Medical Microbiology", year = "2019", volume = "68", number = "2", pages = "119-123", doi = "https://doi.org/10.1099/jmm.0.000885", url = "https://www.microbiologyresearch.org/content/journal/jmm/10.1099/jmm.0.000885", publisher = "Microbiology Society", issn = "1473-5644", type = "Journal Article", keywords = "Treponema pallidum", keywords = "syphilis", keywords = "antimicrobial resistance", keywords = "macrolide resistance", abstract = "We hypothesized that the large global variations in the prevalence of macrolide resistance in Treponema pallidum are related to differences in population-level macrolide consumption. The hypothesis was tested by, at a country-level, regressing the peak prevalence of macrolide resistance against the national macrolide consumption in the year prior to this, controlling for the year of the resistance prevalence estimate. A strong association was found between the per capita consumption of macrolides and macrolide resistance (coefficient 0.7, 95 % confidence interval 0.2–0.12, P=0.009).", }