RT Journal Article SR Electronic(1) A1 Kenyon, ChrisYR 2019 T1 Prevalence of macrolide resistance in Treponema pallidum is associated with macrolide consumption JF Journal of Medical Microbiology, VO 68 IS 2 SP 119 OP 123 DO https://doi.org/10.1099/jmm.0.000885 PB Microbiology Society, SN 1473-5644, AB We hypothesized that the large global variations in the prevalence of macrolide resistance in Treponema pallidum are related to differences in population-level macrolide consumption. The hypothesis was tested by, at a country-level, regressing the peak prevalence of macrolide resistance against the national macrolide consumption in the year prior to this, controlling for the year of the resistance prevalence estimate. A strong association was found between the per capita consumption of macrolides and macrolide resistance (coefficient 0.7, 95 % confidence interval 0.2–0.12, P=0.009)., UL https://www.microbiologyresearch.org/content/journal/jmm/10.1099/jmm.0.000885