1887

Abstract

Reports of a new severe respiratory disease, now defined as severe acute respiratory syndrome (SARS), began to emerge from Guangdong, in southern China, in late 2002. The condition came to international attention through an explosive outbreak in Hong Kong in March 2003. Cases appeared throughout South-East Asia and in Toronto, the spread of SARS being accelerated by international air travel. A global emergency was declared by the World Health Organization, bringing together an international team of epidemiologists, public health physicians and microbiologists to study and contain the disease. This response has enabled the nature of the infectious agent to be identified, its mode of transmission to be established and diagnostic tests to be created rapidly.

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2003-08-01
2024-04-20
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References

  1. Anand K, Ziebuhr J, Wadhwani P, Mesters J. R, Hilgenfeld R. 2003; Coronavirus main proteinase (3CLpro) structure: basis for design of anti-SARS drugs. Science 300:1763–1767 [CrossRef]
    [Google Scholar]
  2. Booth C. M, Matukas L. M, Tomlinson G. A. 18 other authors 2003; Clinical features and short-term outcomes of 144 patients with SARS in the Greater Toronto area. JAMA 289:2801–2809 [CrossRef]
    [Google Scholar]
  3. CDC 2003; Updated interim surveillance case definition for Severe Acute Respiratory Syndrome (SARS) – United States, April 29, 2003. Morbid Mortal Weekly Rep 52:391–393
    [Google Scholar]
  4. Cho K. O, Hoet A. E, Loerch S. C, Wittum T. E, Saif I. J. 2001; Evaluation of concurrent shedding of bovine coronavirus via the respiratory tract and enteric route in feedlot cattle. Am J Vet Res 62:1436–1441 [CrossRef]
    [Google Scholar]
  5. Donnelly C. A, Ghani A. C, Leung G. M. 16 other authors 2003; Epidemiological determinants of spread of causal agent of severe acute respiratory syndrome in Hong Kong. Lancet 361:1761–1761 [CrossRef]
    [Google Scholar]
  6. Drosten C, Günther S, Preiser W. 22 other authors 2003; Identification of a novel coronavirus in patients with severe acute respiratory syndrome. N Engl J Med 348:1967–1976 [CrossRef]
    [Google Scholar]
  7. Fouchier R. A, Kuiken T, Schutten M. 7 other authors 2003; Aetiology: Koch's postulates fulfilled for SARS virus. Nature 423:240– 240 [CrossRef]
    [Google Scholar]
  8. Health Canada 2003; Health Canada statement on release of Health Canada and the US Centers for Disease Control and Prevention preliminary report . Published online 15 May 2003 http://www. hc-sc.gc.ca/english/media/releases/2003/sars_statement.htm
  9. Health Protection Agency 2003; SARS update – laboratory testing shows confirmed case . Published online 15 May 2003 http://www.hpa.org.uk/news/150503_sars.htm
  10. Hong Kong Department of Health 2003; Outbreak of severe acute respiratory syndrome (SARS) at Amoy Gardens, Kowloon Bay, Hong Kong. Main findings of the investigation . Published online 17 April 2003 http://www.info.gov.hk/info/ap/pdf/amoy_e.pdf
  11. Hsu L.-Y, Lee C.-C, Green J. A. 7 other authors 2003; Severe acute respiratory syndrome (SARS) in Singapore: clinical features of index patient and initial contacts. Emerg Infect Dis 9:713–717 [CrossRef]
    [Google Scholar]
  12. Khan A. S, Tshioko F. K, Heymann D. L. 16 other authors 1999; The re-emergence of Ebola hemorrhagic fever, Democratic Republic of the Congo, 1995.Commission de Lutte contre les Epidemies a Kikwit. J Infect Dis 179:Suppl. 1S76–S86 [CrossRef]
    [Google Scholar]
  13. Koren G, King S, Knowles S, Phillips E. 2003; Ribavirin in the treatment of SARS: a new trick for an old drug?. Can Med Assoc J 168:1289–1292
    [Google Scholar]
  14. Ksiazek T. G, Erdman D, Goldsmith C. S. 23 other authors 2003; A novel coronavirus associated with severe acute respiratory syndrome.SARS Working Group. N Engl J Med 348:1953–1966 [CrossRef]
    [Google Scholar]
  15. Lee N, Hui D, Wu A. 11 other authors 2003; A major outbreak of severe acute respiratory syndrome in Hong Kong. N Engl J Med 348:1986–1994 [CrossRef]
    [Google Scholar]
  16. Marra M. A, Jones S. J. M, Astell C. R. 56 other authors 2003; The genome sequence of the SARS-associated coronavirus. Science 300:1399–1404 [CrossRef]
    [Google Scholar]
  17. Parry J. 2003; SARS in China spreads from Beijing to poorer inland provinces. BMJ 326:1056–1056 [CrossRef]
    [Google Scholar]
  18. Peiris J. S. M, Lai S. T, Poon L. L. M. 13 other authors 2003; Coronavirus as a possible cause of severe acute respiratory syndrome. Lancet 361:1319–1319 [CrossRef]
    [Google Scholar]
  19. Poutanen S. M, Low D. E, Henry B. 17 other authors 2003; Identification of severe acute respiratory syndrome in Canada. N Engl J Med 348:1995–2005 [CrossRef]
    [Google Scholar]
  20. Rota P. A, Oberste M. S, Monroe S. S. 32 other authors 2003; Characterization of a novel coronavirus associated with severe acute respiratory syndrome. Science 300:1394–1399 [CrossRef]
    [Google Scholar]
  21. Seto W. H, Tsang D, Yung R. W, Ching T. Y, Ng T. K, Ho M, Ho L. M, Peiris J. S. 2003; Effectiveness of precautions against droplets and contact in prevention of nosocomial transmission of severe acute respiratory syndrome (SARS). Lancet 361:1519–1520 [CrossRef]
    [Google Scholar]
  22. So L. K, Lau A. C. W, Yam L. Y. C, Cheung T. M. T, Poon E, Yung R. W. H, Yuen K. Y. 2003; Development of a standard treatment protocol for severe acute respiratory syndrome. Lancet 361:1615–1617 [CrossRef]
    [Google Scholar]
  23. Tsang K. M, Ho P. L, Ooi G. C. 13 other authors 2003; A cluster of cases of severe acute respiratory syndrome in Hong Kong. N Engl J Med 348:1977–1985 [CrossRef]
    [Google Scholar]
  24. WHO 2003a; First data on stability and resistance of SARS coronavirus compiled by members of WHO laboratory network . Published online 4 May 2003 http://www.who.int/csr/sars/survival_2003_05_04/en/ index.html
  25. WHO 2003b; Severe acute respiratory syndrome: change in status in Toronto (Canada). WHO Wkly Epidemiol Rec 78:169–180
    [Google Scholar]
  26. Wong K. T, Antonio G. E, Hui D. S. C. 9 other authors 2003; Thin-section CT of severe acute respiratory syndrome: evaluation of 73 patients exposed to or with the diseases. Radiology (in press http://radiology.rsnajnls.org/cgi/content/abstract/2283030541v1
    [Google Scholar]
  27. Zhao Z, Zhang F, Xu M. 9 other authors 2003; Description and clinical treatment of an early outbreak of severe acute respiratory syndrome (SARS) in Guangzhou, PR China. J Med Microbiol 52:715–720 [CrossRef]
    [Google Scholar]
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