CTX-M-producing Salmonella spp. in Hong Kong: an emerging problem
Jin, Yujuan and Ling, J. M.,, 55, 1245-1250 (2006),
doi = https://doi.org/10.1099/jmm.0.46637-0,
publicationName = Microbiology Society,
issn = 0022-2615,
abstract= Two Salmonella enterica serovar Typhimurium isolates and one S. enterica serovar Enteritidis isolate that were resistant to 4 μg cefotaxime ml−1 and produced CTX-M-type extended-spectrum β-lactamases (ESBLs) were characterized from patients in Hong Kong during 2003–2004. The S. Typhimurium strain isolated in 2003 produced a CTX-M-9 ESBL and harboured a bla CTX-M-9 gene that was associated with a class I integron-containing gene cassette and orf513 similar to those of In60. The second S. Typhimurium strain and the S. Enteritidis strain, both isolated in 2004, produced CTX-M-14; the former also produced TEM-1. The bla CTX-M-14 gene in these two isolates was associated with the insertion sequence ISEcp1. The CTX-M genes were present on a transferable plasmid of 62, 70 or 92 kb. PFGE of XbaI-restricted total DNA from the two S. Typhimurium isolates indicated that they were not clonally related. These three isolates were also resistant to one of the other non-β-lactam antimicrobial agents tested. This is the first report of a CTX-M-9 ESBL in Salmonella in Hong Kong and the presence of bla CTX-M-9 and bla CTX-M-14 in S. Typhimurium.,
language=,
type=